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Michael Brantley, who had shoulder surgery a month ago, could miss significant time next season, Fanrag Sports' Jon Heyman reports.

Impact

Per Heyman's report, Brantley's shoulder muscle was re-anchored to the bone – a serious procedure that could cost him more time than initially believed. In response to Heyman's report, Brantley said, "maybe (Heyman) knows something I don't," according to MLB.com's Jordan Bastian. The Indians maintain that the expected recovery time is four months, which would mean Brantley would be ready for spring training. This is a murky situation that should continue to develop during the offseason, but those who own Brantley in keeper leagues should be aware that he may not be ready for Opening Day next year.

Kole Calhoun went 2-for-4 with a two-run homer in a win over the A's on Wednesday.

Impact

Calhoun seemed to hit a wall in July and August, but has really picked up to the pace to close out the season, as he is slugging .591 in his last 88 at-bats. The fact that he has yet to reach the 20-homer mark is likely disheartening to owners, but he increased his walk rate by more than three percent from 2015, and should remain a solid late-round option on 2017 draft boards.

Yasmany Tomas was a late scratch Thursday with a stiff neck.

Impact

It's unclear how serious the injury is, but he should be considered day-to-day for now with just three games remaining this season after Thursday's affair. Mitch Haniger was added to the lineup in Tomas' place.

Given the extent of Wilson Ramos' knee injury, he is unsure if he will be able to play in the National League in 2017, MLB.com's William Ladson reports. "Unfortunately this injury… may affect whether I am able to stay with a NL team," Ramos said.

Impact

He is expected to have surgery on a torn ACL this weekend, and it's the surgery could also reveal a torn meniscus, which would add to the length of time he will miss. Ramos is going to be a free agent this winter, and it sounds like there is a very real chance that he will be forced to sign with an American League team so that he can be deployed as a designated hitter, at least in 2017. It's unclear whether this means he might be completely done as a catcher, or whether he simply won't be able to catch initially when he returns at some point next summer. Needless to say, his value in dynasty leagues has taken a huge hit because of this unfortunate knee injury.

A.J. Cole is still expected to start Friday's game against the Marlins while he appeals his suspension, CSN Mid-Atlantic's Chase Hughes reports.

Impact

He was suspended for five games for intentionally throwing at Jung Ho Kang over the weekend, but as he is appealing, the suspension is unlikely to be enforced in time for him to miss Friday's scheduled start.

The Nationals expect to get Daniel Murphy (glute) back for Game 1 of the NLDS on Oct. 7, the Washington Post's Chelsea Janes reports. "We expect him to be ready for the 7th," manager Dusty Baker said.

Impact

This certainly sounds like Murphy won't return during the regular season. Wilmer Difo and Stephen Drew should continue to split time at the keystone over the final four games.

Miguel Cabrera (knee) remains in the lineup Thursday, hitting third and manning first base against the Indians.

Impact

He hit a home run and narrowly missed hitting a second big fly in Wednesday's rain-shortened game, and while manager Brad Ausmus admitted after the game that Cabrera is hobbled by a knee issue, it seems unlikely he will miss time as long as the Tigers stay in the postseason hunt. They enter Thursday one game back of the Orioles in the hunt for the second wild card spot in the American League.

Surgery on Wilson Ramos' torn ACL could reveal possible meniscus tears as well, FOX Sports' Ken Rosenthal reports.

Impact

He expects to have surgery to repair the ACL tear this weekend, and it sounds like the extent of the injury could go beyond the ACL tear. Ramos can safely be ruled out for the first month or two of the 2017 season, and if surgery reveals further damage to his knee, he could be out even longer. This will obviously have a major impact on his free agency this winter, but it still seems like the Nationals are an ideal fit, as they don't have a solid replacement if he were to leave and he has developed a solid rapport with the pitching staff.

Danny Salazar threw a 30-plus pitches off a mound Wednesday, and appears on track to be available out of the bullpen in the ALDS, MLB.com's Jordan Bastian reports.

Impact

He only threw fastballs and changeups, as those would be the two pitches Salazar would use as a reliever. Apparently it hurts his arm too much to throw curveballs. Depending on how deep the Indians go in the postseason, there's a chance Salazar could make a start at some point, but it would likely be a shortened start, the Cleveland Plain Dealer's Paul Hoynes reports.

Jameson Taillon limited the Cubs to one run on one hit and three walks in six innings Wednesday. He struck out four.

Impact

The rookie ended his campaign on a high note, allowing only a first-row homer to Anthony Rizzo. The right-hander emerged as the team's ace, compiling a 3.38 ERA and 1.12 WHIP in 104 innings. Including minor league action, he totaled 165.2 innings after missing the two previous seasons. The workload didn't slow Taillon down and he's put himself in position for an even greater role in 2017.

Carlos Santana is out of Thursday's lineup against the Tigers, the Akron Beacon Journal's Ryan Lewis reports.

Impact

There is a solid chance that Thursday's game will be rained out, but Santana will get the day off either way. If the game does get played, Jesus Aguilar will start at first base and hit seventh while Mike Napoli gets the nod at DH in the cleanup spot.

Jason Kipnis is out of Thursday's lineup against the Tigers, the Akron Beacon Journal's Ryan Lewis reports.

Impact

There is a solid chance that Thursday's game will get rained out, in which case the two teams may need to make the game up Monday. If they are somehow able to squeeze the game in, Michael Martinez will start at second base for the Indians and hit ninth Thursday.

Welington Castillo is out of Thursday's lineup against the Nationals, CSN Mid-Atlantic's Chase Hughes reports.

Impact

He started the last seven games for the Diamondbacks, but will be replaced behind the dish by Tuffy Gosewisch on Thursday. Castillo mad significant gains in batting average and OBP this season over his 2015 numbers, but his owners likely drafted him with hopes of him replicating the 19 homers he hit last year, so the fact that he only has 14 long balls on the season comes as something of a disappointment.

Daniel Murphy (glute) is out of Thursday's lineup against the Diamondbacks, CSN Mid-Atlantic's Chase Hughes reports.

Impact

Murphy will miss his eighth game in a row with the glute strain, and it remains to be seen if he will be able to return during the regular season. Wilmer Difo will start at second base and hit second Thursday.

Evan Gattis went 2-for-4 with his 32nd home run of the season during Wednesday's 12-4 loss to Seattle.

Impact

Gattis, who took Mariners reliever Nick Vincent deep for a solo shot in the sixth inning, has already got the first 30-homer season of his career under his belt. With three games left to play in the regular season, he'll look to finish with career-best marks in OBP (.318), SLG (.827) and ISO (.260).

Bryce Harper (thumb) is out of Thursday's lineup against the Diamondbacks, CSN Mid-Atlantic's Chase Hughes reports.

Impact

This doesn't come as a major surprise, as the Nationals are being cautious with their star right fielder with the division sewn up. Thursday marks the fourth game in a row that Harper will miss with the thumb injury, with Michael Taylor getting the start in right field.

Alex Bregman went 1-for-4 with an RBI in his return to the lineup Wednesday against the Mariners.

Impact

Making his first start since Sept. 14 after dealing with a hamstring injury, Bregman was back in the two-hole and delivered an RBI single in the fifth inning. Prior to his injury, the 22-year-old was on fire, hitting .316 with three home runs and 12 RBI over 13 games in September. His return to the lineup is a welcome sight for the Astros, who are barely clinging onto playoff hope. However, another loss or Orioles win would eliminate them from contention.

Hyun Soo Kim entered as a pinch hitter in the top of the ninth inning Wednesday. He hit a game-winning two-run homer off Toronto's closer Roberto Osuna.

Impact

Kim, who refused an option to the Minor Leagues this spring, has developed into one of the Orioles' most consistent – and popular – players. He delivered the biggest hit of his young MLB career on Wednesday, pinch hitting for Nolan Reimold. Kim sent the ninth pitch he saw from Osuna into the O's bullpen for the go-ahead drive, his sixth homer of the season.

Brett Cecil picked up his eighth hold of the season, pitching one inning and striking out two Wednesday against Baltimore.

Impact

The southpaw was called upon in a pressing spot on Wednesday, entering with a pair of runners on base and one out in the top of the seventh. Cecil successfully work around the trouble while extending his streak to 15 straight scoreless outings. The 30-year-old should continue getting opportunities to pitch in high-leverage situations with Joaquin Benoit possibly out for the season because of a torn left calf muscle. Cecil has been a rare bright spot in the Jays' struggling bullpen during the final month.

Although he earned his 22nd hold of the season, Jason Grilli contributed to the Orioles' comeback win by allowing two hits, including a solo homer, over 0.2 innings Wednesday.

Impact

Grilli is just one of the Jays' relievers that has struggled in recent weeks. The righty has allowed five runs over his last inning of work (he recorded just one out while surrendering four runs in his last appearance), and after starting September with a 3.08 ERA, that mark has ballooned to 4.01.