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Tyron Smith (back) is considered to be a game-time decision for Sunday's matchup against the 49ers, DallasSports.com reports.

Impact

Smith missed Week 3's win over the Redskins, and subsequently sat out of practice this week due to his sore back. Given his absence from practice, the starting left tackle was thought to be unlikely to suit up Sunday. However, there now appears to be optimism regarding his status due to his progression throughout the week. Smith now figures to be a game-time decision. Chaz Green still projects to take his spot in the starting lineup if he is unable to go.

Kevin Norwood (hip) was released from the Panthers' injured reserve list on Friday, Bob Condotta of The Seattle Times reports.

Impact

Norwood, a 2014 fourth-round selection by the Seahawks, has been nursing a hip pointer since Carolina's fourth preseason contest. He's now eligible to sign elsewhere.

Pharoh Cooper is expected to play against the Cardinals on Sunday, Alden Gonzalez of ESPN reports.

Impact

Cooper is not listed on the injury report for Week 4, and he said his left shoulder is pain free when he runs. He could begin to eat into No. 3 receiver Brian Quick's targets as early as Sunday. Additionally, Tavon Austin (shoulder) and Kenny Britt (thigh) are both listed as questionable for the Week 4 contest. Still, it will likely take some time for Cooper to acclimatize to the offense and garner many looks in the passing attack.

Nelson Spruce was not included on the Week 4 injury report and could play against the Cardinals on Sunday, Alden Gonzalez of ESPN reports.

Impact

With both Tavon Austin (shoulder) and Kenny Britt (thigh) questionable for the game, Spruce could be active and make his NFL debut Sunday. However, the undrafted free agent has been out since the preseason opener with a knee injury and is well down the depth chart. His offensive snaps are likely to be limited if he's active.

William Hayes is listed as doubtful for Sunday's game due to an ankle injury.

Impact

Hayes did not practice this week and is a game-time decision against the Cardinals, according to head coach Jeff Fisher. Hayes' status will be revealed before the game Sunday, and Ethan Westbrooks or Eugene Sims could see more action if Hayes is sidelined.

E.J. Gaines is not listed on the Week 4 injury report and expected to play against the Cardinals on Sunday, Alden Gonzalez of ESPN reports.

Impact

Gaines started 15 games during his rookie season in 2014, and once back to full speed following his thigh injury, he's a candidate to start at right cornerback opposite Trumaine Johnson. Coty Sensabaugh, Troy Hill and Lamarcus Joyner could see fewer defensive snaps with Gaines back in the fold.

Chris Ivory (ankle/knee) is pleased with his conditioning as the Jaguars prepare to face the Colts in London, the Florida Times-Union reports.

Impact

Despite missing the first two weeks with a still-undisclosed medical issue, Ivory seems to be at close to full strength ahead of Sunday's game. He was limited at Wednesday's practice due to minor knee and ankle injuries, but after logging full sessions both Thursday and Friday, his availability isn't in any question. With Ivory's health no longer the primary concern, attention shifts to his team's complete inability to open holes in the running game. Ivory gained just 14 yards on 12 carries in last week's loss to Baltimore, and T.J. Yeldon is averaging a meager 2.5 yards on his 34 totes this season. On a more optimistic note, Yeldon only took six carries last week, and the Colts aren't exactly a defensive powerhouse.

Senio Kelemete has been ruled out for Week 4 due to a hamstring injury.

Impact

It's unclear how Kelemete injured his hamstring but it was enough to keep him out of practice this past week. The absence of the backup guard shouldn't impact the offense at all.

Terron Armstead (knee) has been ruled out for Sunday's Week 4 contest.

Impact

Armstead missed last week's game due to his knee injury and was unable to practice this week as he continues to recover. Look for Tony Hills to start in his place once again.

Dominique Easley is listed as questionable for Week 4 due to illness.

Impact

Easley missed time this week but was able to practice in full on Friday, making it very likely he's over his illness and healthy enough to play on Sunday despite being a game-time decision.

Lamarcus Joyner is questionable for Sunday's game due to a toe injury.

Impact

Joyner went through a full progession in practice this week, not participating on Wednesday before being limited on Thursday and practicing in full on Friday. The full practice is an encouraging sign for his status. Look for Troy Hill to get the start if Joyner is held out.

Sammy Watkins (foot) isn't scheduled for surgery, but he'll visit with Dr. Robert Anderson to be sure, NFL.com's Ian Rapoport reports.

Impact

Watkins was placed on injured reserve Friday, officially ruling him out for at least the next eight weeks. He didn't have any structural damage at last check, but the pain in his surgically-repaired foot has simply refused to subside. Assuming no structural damage is found, he'll likely spend the next eight weeks resting, with the hope that his foot will feel better if he uses it as little as possible. If he does end up needing some kind of procedure, it would likely spell the end of his season.

Doug Martin (hamstring) has been ruled out for Sunday's game against Denver.

Impact

Martin still hasn't returned to practice and could miss time beyond Sunday, though it could help his cause that the Bucs have an extra day to prepare before facing the Panthers on Monday Night Football in Week 5. Charles Sims will draw another start, this time facing a tough Denver defense after handling 68 of the 90 offensive snaps in a Week 3 loss to the Rams. The Broncos have been surprisingly vulnerable to the run this season, and Sims' receiving ability should ensure he stays involved regardless of the score.

Joe Reitz (back) is questionable for the Colts' Week 4 tilt against the Jaguars, Kevin Bowen of Colts.com reports.

Impact

Reitz was forced to leave last week's game after suffering his back injury in the second quarter. If he's unable to play in Week 4 look for Joe Haeg to fill in for him at tackle.

William Hayes (ankle) is a game-time decision for Sunday's matchup against the Cardinals according to coach Jeff Fisher, ESPN reports.

Impact

Hayes did not practice this week since going down in Week 3. He's doubtful to play, but his status will be confirmed prior to kickoff nonetheless.

Frostee Rucker (knee) will not play in Week 4 against the Buccaneers, Mike Jurecki of Fox Sports 910 reports.

Impact

Rucker did not practice this week after not playing in Week 3. Rodney Gunter projects to start at defensive end once again.

Kareem Martin (knee) is questionable to play in Week 4, Mike Jurecki of Fox Sports 910 reports.

Impact

Martin is yet to make his regular season debut as he works his way back from injury. He appears to have an outside chance of playing on Sunday.

Nate Palmer (knee) is questionable to play in Week 4, Titans' senior writer Jim Wyatt reports.

Impact

Palmer has had a sore knee for several days and even had an MRI, though the results have not been disclosed. If he's unable to play on Sunday look for Sean Spence to see a few extra reps.

Tyvon Branch (groin) is questionable to play in Week 4 against the Buccaneers, Mike Jurecki of Fox Sports 910 reports.

Impact

Branch was limited in practice throughout the week. His status will be confirmed prior to the start of the game.

Dont'a Hightower (knee) is questionable to play in New England's Week 4 game against Buffalo.

Impact

Hightower has missed the Patriots' last two games due to his knee injury but was able to practice in a limited fashion all week and is nearing a return. Look for Elandon Roberts to see extra time once again if Hightower is limited or held out.