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The 49ers ruled Deebo Samuel (hamstring) out for Sunday's game at Seattle, Cam Inman of The San Jose Mercury News reports.

Jordan Reed (knee) could be treated as a game-time decision for Sunday's matchup with Seattle, but coach Kyle Shanahan said the 49ers' other players returning from injured reserve are more likely to play, Keiana Martin of the team's official website reports.

Coach Bruce Arians has called Leonard Fournette his current "nickel" running back, using him in hurry-up and clear passing situations, Greg Auman of The Athletic reports.

Deonte Harris and Tre'Quan Smith are the only healthy wide receivers on the Saints' active roster, Amie Just of The New Orleans Times-Picayune reports.

Tre'Quan Smith and Deonte Harris are the only healthy wide receivers on the Saints' active roster, Amie Just of The New Orleans Times-Picayune reports.

DeeJay Dallas is the only Seattle tailback without an injury designation for Sunday's game against the 49ers, Brady Henderson of ESPN.com reports.

Allen Lazard (core) practiced again Friday, Rob Demovsky of ESPN.com reports.

The Jaguars cut Aldrick Rosas from the practice squad Friday, per the NFL's official transaction log.

Jake Luton will be in the mix to start Week 9 against the Texans if Gardner Minshew (thumb) is unavailable, John Oehser of the Jaguars' official site reports.

Boston Scott will draw the start at running back against Dallas on Sunday, Chris McPherson of the Eagles' official site reports.

Calvin Ridley has been diagnosed with a mid-foot sprain, Ian Rapoport of NFL Network reports.

Tyrod Taylor (chest) is questionable for Sunday's game versus the Broncos.

The Jaguars activated Chris Thompson (illness) from the reserve/COVID-19 list Friday, Aaron Wilson of the Houston Chronicle reports.

Richie James (ankle) is considered doubtful for Sunday's game versus the Seahawks, Eric Branch of the San Francisco Chronicle reports.

Travis Homer (knee) will be a game-time decision for Sunday's matchup with San Francisco, Michael-Shawn Dugar of The Athletic reports.

Jarvis Landry (ribs/hip) doesn't carry an injury designation for Sunday's game against the Raiders after logging a full practice Friday, Scott Petrak of The Chronicle-Telegram reports.

Tyler Higbee (hand) will be a game-time decision Sunday in Miami, Lindsey Thiry of ESPN.com reports.

Jamaal Williams' teammate Aaron Jones (calf) has been ruled out for Sunday's game against Minnesota, Matt Schneidman of The Athletic reports.

Damien Harris (ankle) is listed as questionable for Sunday's game against the Bills after practicing in a limited fashion all week, Mike Reiss of ESPN.com reports.

Tevin Coleman (knee) appears on track to play in Sunday's game against Seattle, but the 49ers haven't announced a decision, Cam Inman of The Bay Area News Group reports.