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Michael Williams injured his leg/knee during Wednesday's minicamp, and was seen walking with crutches on Thursday, Mike Reiss of ESPNBoston.com reports.

Impact

Williams is set to receive a second opinion on his injured leg, but initial indications are pessimistic which could mean the tight end misses some amount of time. Prior to the injury, Williams was projected to fill in as the No. 3 option at tight end behind Rob Gronkowski and Martellus Bennett, but the possible seriousness of Williams' issue could open the door for Clay Harbor to secure that spot with little offseason competition.

D'Joun Smith, who was placed on season-ending IR in December of the 2015 season, suffered a setback with his knee injury this offseason according to Colts GM Ryan Grigson, Mike Chappell of Indysportscentral.com reports.

Impact

Smith appeared in just four games throughout his rookie season after being unable to reach 100 percent following knee surgery earlier in the year. He continues to have issues with the knee, which could impact his status for training camp and beyond, while it's unclear if he'll be back to full health by the time Week 1 rolls around.

Dan Herron signed with the Bills on Thursday, Chris Brown of the team's official site reports.

Impact

Herron will join a crowded backfield in Buffalo, as the team currently has six running backs on the roster in a group that is led by LeSean McCoy. A product of Ohio State, Herron is no stranger to the franchise, as the 27-year-old played in four games for the Bills in 2015, carrying the ball 11 times for 37 yards. After getting released in November, Herron finished up the year with the Colts, averaging 3.0 YPC over six games to finish the year. He'll now return to Buffalo to compete for a roster spot as backfield depth.

Coach Rex Ryan confirmed that EJ Manuel is his clear-cut No. 2 quarterback entering the season, BuffaloBills.com reports. "Unlike last year we're set with a pecking order," Ryan said Wednesday. "Tyrod is the number one guy, EJ is two and Cardale is three. We know that going in."

Impact

Manuel has done very little to match his first-round draft status from 2013, and he may have had one of the league's ugliest quarterbacking performances in a decade during last season's London loss to Jacksonville. That said, Ryan and GM Doug Whaley are sticking by him, and there's something to be said about Manuel's arm strength and familiarity with the Buffalo offense. However, you'll hear an incredibly loud gasp whenever Tyrod Taylor is slow to get up from the Ralph Wilson Stadium turf this fall.

Darren Sproles has reported to practice and resumed his "extensive" role in the Eagles' system, Dave Zangaro of CSN Philadelphia reports.

Impact

Sproles skipped the voluntary portion of the Eagles' offseason program due to family-related issues, but returned to practice Tuesday and participated in both team and position drills, as well as in the special teams portion of practice as a punt returner. The latter is nothing new, as Sproles has been brought back punts for multiple seasons (and has returned a pair for touchdowns each of the past two seasons). Nonetheless, it's reaffirming to hear newly-assigned head coach Doug Pederson declare the almost-33-year-old Sproles as the "primary guy" regarding punt returns, and offensively as "a big part of what we do." Sproles has collected 70 rushing attempts and roughly 50 receptions on average in each of his two years in Philadelphia while operating primarily as a gadget player, but those numbers could rise in a remodeled offense sans DeMarco Murray.

Kellen Davis will miss the remainder of OTAs after undergoing surgery on a torn ligament in his right thumb, Rich Cimini of ESPN.com reports

Impact

According to head coach Todd Bowles, Davis will be ready for the beginning of training camp in late July. The veteran tight end only had three receptions last season but could see an expanded role in 2016 after the Jets cut Jeff Cumberland earlier in the offseason.

Gary Barnidge (abdomen) plans to be ready before training camp.

Impact

Barnidge underwent surgery less than a week ago on a sports hernia, but plans to come into training camp ready to go. The Browns' leader in receptions year ago has said he specifically planned the timing of the surgery. "It was just an opportunity to get it all done and I won't miss any time. That was the purpose of it, so we would get all of this done and then I would be ready to go for training camp and it wouldn't pop in season", Barnidge said Wednesday before Browns practice.

Manny Ramirez has decided to retire from the NFL.

Impact

Ramirez played over eight seasons in the league with the Lions and Broncos. The 33-year-old signed with the Bears as an unrestricted free agent in March, but has now decided to hang up the cleats.

There is no deal in sight for Von Miller and the Broncos to reach a long-term deal despite Denver's six-year, $114.5 million offer, Adam Schefter of ESPN reports.

Impact

Despite the team having until the middle of next month to come to an agreement with the star edge rusher, they curiously imposed a Tuesday deadline for negotiations. The deal is tricky because both sides feel as though they have leverage. Denver can say that it is paying Miller more than any defender in league history and can always fall back on slapping him with the franchise for the next three years for about $55 million total. Miller, on the other hand, was easily the team's best player in the AFC title game and Super Bowl 50 and is entering a market in which Olivier Vernon is making $17 million per year. At the end of the day, it is difficult to picture Miller in a color other than orange in the coming years as there is still time to make a deal and the Broncos have the franchise-tag fallback.

Shaun Suisham is still recovering from a torn ACL on his non-kicking leg, which ended his 2015-16 season, Mark Kaboly of TribLive.com reports.

Impact

Suisham has yet to attempt a kick due to the injury he suffered over 10 months ago, and is unsure if he'll be ready for the late-July start of training camp. Chris Boswell, heading into his sophomore campaign, filled in for Suisham last season, converting 36 of 39 field-goal attempts and 27 of 28 extra-point attempts. The two are expected to compete for the starting job, but even if Suisham isn't able to win back the gig he's held for three seasons, he could find his way onto another team's roster given his impressive track record.

Giovani Bernard signed a three-year, $15.5 million extension with the Bengals on Wednesday.

Impact

Bernard will now be a Bengal through 2019 as he heads into the prime of his career. The 24-year-old rushed for 730 yards and two touchdowns to go along with 49 receptions for 472 yards last season, as he split time with Jeremy Hill.

Mike Scifres signed a one-year contract with the Panthers on Tuesday.

Impact

After being cut by the Chargers, where he spent the previous 13 seasons, Scifres will now head to Carolina to compete with Swayze Waters for the punting job. The 35-year-old averaged 45.3 yards per punt last season.

Dontae Johnson - who suffered an undisclosed leg injury during practice - did not take part in Tuesday's minicamp, the San Francisco Chronicle reports.

Impact

The 49ers didn't offer much information on the nature of the injury, but it doesn't seem serious as Johnson was seen warming up before team activities. Johnson will compete with a slew of new cornerbacks for a prominent role in Chip Kelly's revamped secondary.

Colin Kaepernick (shoulder) returned to practice for the first time this offseason, the San Francisco Chronicle reports.

Impact

Initial reports stated that Kaepernick would be limited to individual drills during the 49ers' three-day minicamp, but he ended up participating in the team's seven-on-seven sessions as well. He wasn't going at 100 percent, but was seen firing the ball close to 50 yards down the field. Kaepernick was also noticeably slimmer, but that was to be expected after not being able to work out during his shoulder rehab. His health, weight and acclimation to Chip Kelly's offense will all be things to monitor this offseason with respect to gauging whether Kaepernick can bounce back in 2016.

LeSean McCoy sat out team drills Wednesday due to a tight hamstring, Mike Rodack of ESPN reports.

Impact

McCoy's absence Wednesday looks to be mostly precautionary, with coach Rex Ryan noting that the hamstring issue is not believed to be serious. Expect to see McCoy back on the field within the next handful of days.

Devontae Booker (knee) is making strides in learning Denver's offense as he recovers from a torn meniscus, the team's official site reports.

Impact

Booker was reportedly a consideration for Denver at the end of the first round, so the team clearly believes that he has the physical skills to be a featured back. The mental aspects of the game could be the biggest adjustment for the young back, something he can improve on even while taking it slow as he recovers from a knee injury. The Broncos handed C.J. Anderson a front-loaded new contract earlier this year - rewarding him for being Denver's best offensive weapon through the playoffs. It might be tough for the rookie to unseat Anderson in Year One, but Ronnie Hillman's role as the No. 2 could be up for grabs.

As details of Aqib Talib's (leg) shooting incident become clearer, the corner could face league or legal discipline the Denver Post reports.

Impact

Talib was fortunate to avoid serious injury, but it's possible that the incident could cost him playing time in the upcoming season anyway. Rumors are circulating that Talib accidently shot himself and - if he was intoxicated - he could have violated Texas law. Even if he avoids charges, his past indiscretions could lead to a suspension. There are a ton of moving parts in this case, but Talib's health is just one factor. Should he miss any time, 2014 first-round pick Bradley Roby figures to see an increased workload.

Mark Sanchez (thumb) is solidifying his place atop Denver's depth chart, 9NEWS reports.

Impact

Though there have been reports touting both holdover Trevor Siemian and rookie Paxton Lynch, the news solidifies what many assumed on draft night - that Sanchez would likely be Denver's Week 1 starter. Sanchez might be new to town, but he reportedly ran a similiar offense at USC, offers the lone veteran presence at the position and has been active in trying to bond with his new teammates. There might be a point during training camp that Lynch or Siemian catches up, but for now, the safe bet is on Sanchez to start the season.

While Andrew Sendejo has lined up next to Harrison Smith at safety on the vast majority of snaps at this week's OTAs, head coach Mike Zimmer says there will be an open competition for the starting safety job next to Smith, the Minneapolis Star Tribune reports.

Impact

The Vikings signed free agent Michael Griffin in the offseason but Zimmer said Antone Exum, Anthony Harris and 2016 seventh-round draft pick Jayron Kearse would also be in the mix. Sendejo struggled in pass coverage last season and would seem to be at risk to lose playing time even if he keeps his starting job. It will be a battle to watch during training camp.

Rob Gronkowski (undisclosed) was one of 13 Patriots players who didn't practice Tuesday at the team's mandatory minicamp, ESPN's Mike Reiss reports.

Impact

The report relays that Gronkowski reported to the minicamp with his teammates and is said to be getting in some work "behind the scenes" as the team proceeds cautiously with the tight end, who is dealing with an "undisclosed physical ailment that isn't considered a long-range concern." Meanwhile, with Gronkowski not participating in practice Tuesday, newcomer Martellus Bennett saw added 1-on-1 time with QB Tom Brady.