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Muhammad Wilkerson (turf toe) is active for Sunday's game against the Patriots.

Impact

Wilkerson, who last played in Week 13 against the Bills, was considered a game-time decision Sunday, and apparently did enough in warmups to warrant getting the start. He comes into the game with 4.5 sacks on the season, though he's had only a half-sack since Week 6.

Cam Newton (back) is active and will start Sunday's game against the Browns, ESPN's Adam Schefter reports.

Impact

Newton has been given the green light by doctors and will be back under center after missing just one game due to his back injury. He will wear a protective vest, but he still may be a bit tender just 12 days after the accident, so he may be more tentative than usual to escape the pocket and make plays happen with his feet. Plus, if the Browns defense is hemorrhaging rushing yards like it did last week, Newton may spend much of the day handing the ball off to Jonathan Stewart.

Julio Jones (hip) will play Sunday against the Saints, according to Albert Breer of NFL Network.

Impact

Jones has not practiced since suffering the injury in Week 14 against the Steelers, but after being listed as questionable, he reportedly showed enough in warmups to be given the green light. He reportedly was a full participant in Saturday's walkthrough, though that's hardly close to a full practice. Fantasy owners shouldn't expect a full workload given how much time he has missed due to the ailment.

Following his morning workout, DeAndre Hopkins (ankle) is reportedly "good to go" for Sunday's game against the Ravens, according to NFL Network's Ian Rapoport.

Impact

Though Hopkins did not practice this week, it appears as though he plans to give it a go Sunday, an outcome that we will confirm – one way or the other – in advance of Sunday's 1:00 ET kickoff.

According to NFL Network's Ian Rapoport, T.Y. Hilton (hamstring) will try to play Sunday against the Cowboys, though the report suggests that such an outcome appears to be a long-shot.

Impact

As Sunday's game approaches, Hilton's status remains cloudy, a tricky situation for fantasy owners, given the Colts' 4:25 ET kickoff. In the event that Hilton sits Sunday, or is limited, Donte Moncrief would be a candidate to see added looks in the team's Week 16 offense.

According to NFL Network's Ian Rapoport, DeMarco Murray is in line to play Sunday against the Colts with a pad on his surgically-repaired left hand.

Impact

Those planning to use Murray this week are still advised to verify his status in advance of Sunday's 4:25 ET kickoff, but it appears as though the running back plans to give it a go. It remains to be seen how Murray will hold up as a pass-blocker Sunday and how effective he might be in the passing game, with Joseph Randle and Lance Dunbar on hand to serve in complementary roles and to spell Murray if he is limited at all as Week 16's game progresses.

The Falcons are optimistic that Julio Jones (hip) will play Sunday against the Saints, according to Albert Breer of NFL Network.

Impact

Jones is officially questionable for the game, but he has yet to practice after suffering the injury Dec. 8. He was a game-time decision in Week 15 but was unable to play, and his lack of practice could indicate that he'll be limited in Sunday's game, if he is cleared to play. Harry Douglas figures to see more targets if Jones is unable to play his normal full workload.

Vernon Davis was not targeted in Saturday's overtime loss to the Chargers.

Impact

Colin Kaepernick through for just 114 yards, but the fact that he didn't look Davis' way even once is the final nail in the coffin on Davis' 2014 fantasy season. He has not caught a pass in back-to-back games.

Phil Dawson made five extra points but missed his only field-goal attempt in Saturday's overtime loss to the Chargers.

Impact

The field goal was a 60-yard try at the end of regulation that would have won it for the 49ers but was so short that it never had a shot. The 39-year-old has made multiple field goals just once in his last five games.

Michael Crabtree (knee) had one catch for five yards in Saturday's overtime loss to the Chargers.

Impact

Crabtree, who came into this game listed as questionable with a knee injury, may have aggravated the injury early on because he hardly played in this contest. He spent much of the game on the sideline with a baseball cap on and only entered the game in overtime after the 49ers lost a couple of other receivers to injury. Given his recent level of output, you're probably better off looking elsewhere for WR help in Week 17.

Colin Kaepernick completed 15 of 24 passes for 114 yards and a touchdown in Saturday's overtime loss to the Chargers. He made his biggest impact on the ground, rushing seven times for 151 yards and another score.

Impact

A measly 4.8 yards per passing attempt isn't going to win any fantasy championships, but fortunately Kaepernick salvaged his fantasy stat line with a breathtaking 90-yard touchdown run in the third quarter. This is now four straight games under 200 passing yards for the 126 million dollar man, so unless he rips off a 90-yard run again next week, it's hard to consider him a strong fantasy option against the Cardinals.

Anquan Boldin was targeted a team-high nine times in Saturday's overtime loss to the Chargers, finishing with seven catches for 61 yards.

Impact

Quarterback Colin Kaepernick threw for just 114 yards, so Boldin did a good job of gobbling up what little receiving yardage was available (only one other 49er had more than nine yards). After a strong season, Boldin is sputtering to the finish, averaging just 39 yards per game over his last four contests.

Frank Gore (concussion) had 26 carries for 158 yards and a touchdown in Saturday's overtime loss to the Chargers.

Impact

Gore made the Chargers defense look ridiculous on his 52-yard touchdown run in the first quarter, and he was his usual punishing and effective self on his other 25 totes. With the 49ers out of playoff contention, Gore is out to prove to teams that he deserves a rich contract as a free agent this offseason, though he may run into trouble next week against the Cardinals' stout front seven.

Dontrelle Inman had seven catches for 79 yards in Saturday's overtime win over the 49ers.

Impact

Who? The 25-year-old journeyman had not caught an NFL pass since coming out of Virginia in 2010, but he took advantage of Keenan Allen's absence Saturday night to play a key role for the Chargers. It's a great story, but any fantasy owners still looking for Week 17 options should probably find a receiver with more of a proven track record.

Donald Brown had four carries for 12 yards and one catch for four yards in Saturday's overtime win over the 49ers.

Impact

Brown got the short end of the stick in the Chargers' three-man Ryan Mathews replacement committee, finishing with fewer carries than both Brandon Oliver (13) and Ronnie Brown (seven). Regardless of whether Mathews plays in Week 17, Donald Brown can't be trusted in most leagues.

Eddie Royal was targeted a team-high 12 times in Saturday's overtime win over the 49ers, leading the Chargers with 10 catches for 94 yards and a touchdown.

Impact

Royal was a crucial part of the Chargers' big second-half comeback, especially his 17-yard catch on a critical fourth-and-8 that kept San Diego's game-tying drive alive. He seemed to be the player who benefitted most from Keenan Allen's absence, so if you are in a league that plays through Week 17, keep an eye on Allen's status leading up to next Sunday's matchup with the Chiefs. If Allen is out again, Royal stands to benefit.

Branden Oliver had a team-high 13 carries for 53 yards in Saturday's overtime win over the 49ers. He added three receptions for 28 yards.

Impact

It was a three-headed rushing attack for the Chargers, but Oliver received more than half the carries (13 of 24). It's still too early to know much about Ryan Mathews' health status for Week 17, but if he is forced to miss another game, Oliver would be an appealing flex play against the Chiefs, who have allowed four different opposing running backs to rush for 100-plus yards in the last five weeks.

Malcom Floyd had four receptions for 50 yards and a touchdown in Saturday's 38-35 overtime victory over the 49ers.

Impact

With Keenan Allen out, Floyd was targeted 10 times, his highest total of the season. Allen may be out next week as well, but Floyd will be working against a Chiefs defense that has been outstanding at shutting down opposing wide receivers this season.

Nick Novak made his only field-goal attempt, a 40-yard game-winner, and connected on all five extra-point tries in Saturday's 38-35 overtime win in San Francisco.

Impact

After missing two kicks in last week's loss, Novak made good this week, putting the finishing touch on San Diego's improbable, season-saving comeback. However, a matchup against a stout Kansas City defense awaits in Week 17.

Philip Rivers (chest/back) threw three interceptions but was able to rally the Chargers to a huge second-half comeback for a 38-35 overtime victory in San Francisco on Saturday night. He completed 33 of 54 passes for 356 yards and four touchdowns.

Impact

The Chargers found themselves down 28-7 at the break, thanks in large part to two Rivers interceptions, one of which was returned 49 yards for a touchdown. However, the quarterback was brilliant after halftime, leading San Diego to four scoring drives and converting on two crucial fourth downs to keep the Chargers' hopes alive. It was a gutty performance, but it will be nearly impossible for him to repeat these kinds of numbers next week against a Chiefs pass defense that has allowed just two quarterbacks all year to top 250 passing yards and none to eclipse 300.