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Pharoh Cooper (shoulder) is doubtful for Sunday's game against Tampa Bay, ESPN's Alden Gonzalez reports.

Impact

A limited practice participant throughout the week, Cooper isn't quite ready for his NFL debut in the wake of an extended absence. Once he's up to speed, which could happen as soon as next week, he may get a shot push an unproductive Brian Quick for the No. 3 wide receiver role.

Evan Mathis (toe) will not be available for the Cardinals' Week 3 matchup against the Bills, Kent Somers of AZCentral.com reports.

Impact

This appears to be a separate injury from the one that put his Week 2 status in question, as Mathis is reportedly now dealing with a turf toe instead of a mid-foot sprain. In his absence, Cole Toner projects to slide into the starting lineup at right guard.

Doug Baldwin (knee) doesn't have an injury designation on the final injury report of the week.

Impact

After returning to a full practice Thursday, the Seahawks' top receiver didn't seem to be in any danger of missing Sunday's game against San Francisco. Friday's injury report merely confirms that Baldwin will indeed take the field.

Nick Vannett (ankle) is listed as doubtful for Sunday's game against San Francisco.

Impact

With Jimmy Graham and Luke Willson both healthy, Vannett's availability is of little consequence to Seattle. The rookie will likely start his career with a third consecutive absence.

Tyler Lockett (knee) is listed as questionable for Sunday's game against San Francisco.

Impact

Despite what the injury designation might seem to suggest, head coach Pete Carroll said Friday that Lockett is ready to play, according to Curtis Crabtree of Sports Radio KJR. Lockett was a limited practice participant Wednesday and a full participant Friday, leaving little question regarding his Sunday availability.

Quincy Enunwa (ribs) was a full participant in Friday's practice and could stand to benefit if teammate Brandon Marshall (knee) misses Sunday's game against the Chiefs, The Star-Ledger reports.

Impact

Enunwa has impressed through the Jets' first two games of the season, totaling 13 receptions on 14 targets for 146 yards and a touchdown. In the absence of a recognizable tight end, his role as the Jets' No. 3 wideout is increasingly useful in fantasy leagues, and Enunwa could be featured even more heavily if Marshall is unable to play Sunday. In any event, Enunwa's full practice Friday suggests his injury poses little concern regardless of his role this weekend.

C.J. Prosise (hand) is listed as questionable for Sunday's game against San Francisco.

Impact

While the hand injury hasn't impacted his practice participation, Prosise is seemingly in real danger of missing a second straight game, as the injury impacts his ability to catch, which is his primary source of value to the team. With Thomas Rawls (lower leg) listed as doubtful, Christine Michael may have a chance to serve as a true three-down workhorse.

Christine Michael's teammate Thomas Rawls (lower leg) is listed as doubtful for Sunday's game against San Francisco.

Impact

With Rawls likely sidelined and C.J. Prosise (questionable-hand) potentially limited or unavailable, Michael is set for a heavy workload that could include the vast majority of snaps on obvious passing downs, in addition to dominance of the rushing attempts. Given the role and opponent, Michael is shaping up as a clear top-10 option at running back for Week 3.

Austin Howard (ankle) will not play in Week 3.

Impact

Howard was a full participant in practice leading up to Week 2, but appears to have aggravated the ankle injury that forced him from the Raiders' season opener as he did not practice in any capacity throughout the week.

Thomas Rawls (lower leg) is listed as doubtful for Sunday's game against San Francisco.

Impact

Head coach Pete Carroll was optimistic earlier in the week, but he changed his tune during a Friday morning radio interview, and Rawls then missed a third consecutive practice. With the injury lingering longer than expected, it appears Christine Michael will take on a heavy workload for a game in which the Seahawks are heavily favored. What's more, passing-down back C.J. Prosise (hand) is listed as questionable, potentially setting Michael up for a full three-down role. Fifth-round rookie Alex Collins could also be involved.

Menelik Watson (groin) is questionable to play in Week 3.

Impact

Watson returned to practice on Wednesday after suffering a groin injury during Oakland's regular season opener. While he was limited on both Wednesday and Thursday, he fully participated on Friday and seems likely to suit up for Sunday's tilt against the Titans.

Matt McCants (knee) has been ruled out for Sunday's matchup with the Titans.

Impact

McCants will remain sidelined for the second straight week after going down in the Raiders' season opener. It's uncertain whether he could return Week 4.

Kenyan Drake is expected to share reps with starter Jay Ajayi in teammate Arian Foster's (groin) absence Sunday against the Browns, ESPN's James Walker reports.

Impact

Drake scored his first career touchdown on one of his two rushes for 12 yards last week versus the Patriots, and he'll aim to build on that outing in an expanded role against the Browns this Sunday. While Ajayi will start with Foster sidelined, Drake should see a decent amount of snaps himself, conceivably earning more touches if he can outproduce Ajayi over the course of the game.

David Amerson (concussion) is questionable to play in the Raiders' Week 3 matchup against the Titans.

Impact

Amerson went down with a concussion during Oakland's Week 2 game, but cleared the NFL's concussion protocol on Thursday before practicing in full on Friday. While his status will be confirmed prior to kickoff, the NC State product appears likely to suit up.

Jay Ajayi is expected to start Sunday against the Browns in teammate Arian Foster's (groin) absence, ESPN's James Walker reports.

Impact

Ajayi's first career start will come after he rushed five times for 14 yards and caught four passes for 31 yards last weekend against the Patriots. That followed him being left home for the season opener in Seattle, but Ajayi has seemingly redeemed himself enough to claim the Dolphins' first-team job for this Sunday. Although Miami's running game is averaging just 3.7 yards per rush and rookie Kenyan Drake should share touches with him, Ajayi has a good opportunity to improve his stock by potentially helping the Dolphins earn their first win Sunday.

Taiwan Jones (knee) is questionable to play in the Raiders' Week 3 matchup against the Titans.

Impact

Jones fully participated in Friday's practice after being limited on Wednesday and Thursday. However, even if he is ultimately given the green light to play, he has received fewer carries thus far into the season than fellow backups DeAndre Washington and Jalen Richard despite Jones' status as the ostensible No. 2 tailback.

Lavonte David (shoulder) is listed as questionable for Sunday against Los Angeles, Roy Cummings of WFLA Channel 8 reports.

Impact

If the 'probable' designation still existed, David would almost certainly have it. He was a full practice participant this week and can still be safely deployed as a high-end IDP.

Willie Young (knee) is questionable to play Week 3 against the Cowboys.

Impact

Young appears to have suffered a knee injury during Thursday's practice and remained limited during Friday's session. Sam Acho projects to fill his place in the starting lineup if Young is unable to give it a go.

Cecil Shorts (hamstring) has been ruled out for Sunday's game against Los Angeles, Roy Cummings of WFLA Channel 8 reports.

Impact

Even if he were healthy, which hasn't happened often the past few years, Shorts would likely just be the No. 4 or 5 wideout in Tampa Bay. His absence could leave a few more snaps for Russell Shepard and/or Freddie Martino.

Luke Stocker (ankle) has been ruled out for Sunday's game against Los Angeles, Roy Cummings of WFLA Channel 8 reports.

Impact

Even with Austin Seferian-Jenkins no longer on the team, Stocker is unlikely to draw more than a target or two per game, as his role will still largely revolve around blocking. Cameron Brate and Brandon Myers are the real candidates to benefit from ASJ's release.