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Mike Evans has tallied 17 first downs over the season's first three weeks, more than any other player in the league, Jenna Laine of ESPN.com reports.

Impact

The third-year receiver is off to a good start with respect to putting his drop-laden 2015 behind him, as he's looked like a much more consistent receiver throughout the first three weeks of the new campaign. Evans also has posted a 75 percent (3-for-4) success rate in the red zone, after hauling in only two of 13 targets (15.4 percent) inside the 20 last season. With a whopping 39 targets, touchdowns in each contest, and a solid 14.3 YPC to date, the 23-year-old seems primed for a standout campaign.

Robert Ayers has shed the cast on his ankle but is still not practicing, Jenna Laine of ESPN.com reports.

Impact

After exiting the Bucs' Week 2 tilt versus the Cardinals with is injury, Ayers missed all of practice last week, as well as the Week 3 loss to the Rams. The veteran defensive end's absence resulted in an uptick in William Gholston's tackle numbers and didn't seem to hinder Tampa's stalwart run defense, as they still managed to contain Todd Gurley to the tune of 3.1 YPC. If he logs another DNP on Thursday, Ayers will seemingly be on his way to missing another contest.

Kenny Vaccaro (ankle) expects to play in Sunday's matchup with the Chargers, The Times-Picayune reports.

Impact

Vaccaro injured his ankle in Week 2's loss to the Giants, and subsequently missed the following game. He indicated his absence was more of a coaching decision however, as he felt he could have played through it. The starting strong safety appears to be on track for a return Sunday.

Nelson Spruce (knee) was a full participant at Wednesday's practice, Gary Klein of the Los Angeles Times reports.

Impact

Spruce has been out of action since Week 1 of the preseason due to a knee injury. His full participation at practice Wednesday seems to indicate he is trending toward making his season debut on Sunday. However, he is buried on the team's depth chart, so his opportunities to take the field will be limited.

Marcus Cromartie (ankle) was a full participant at Wednesday's practice.

Impact

Cromartie's ability to give it a full go Wednesday indicates that his ankle injury is largely behind him. If he is able to play Sunday against the Cowboys, Cromartie will provide depth at free safety behind starter Eric Reid.

Garrett Celek was limited in Wednesday's practice due to a back injury.

Impact

Celek took over as the 49ers' starting tight end after Vance McDonald exited Week 3's contest with a hip injury. With McDonald McDonald unlikely to be available against the Cowboys on Sunday, Celek will likely get another crack at starting tight end as long as his back injury isn't of major concern. Keep tabs on Celek's progress as the week goes on, as he could be a nice streaming against a Cowboys' defense that has allowed 82 yards per game to tight ends this season.

Pharoh Cooper (shoulder) was able to practice without limitations on Wednesday, Gary Klein of the Los Angeles Times reports.

Impact

The rookie returned to practice last week after dealing with a shoulder injury, but has yet to take the field this season. He appears to be trending toward making his debut on Sunday given his full participation in Wednesday's practice. His role figures to be limited however, as he is still behind Kenny Britt, Tavon Auston, and Brian Quick on the depth chart, and it could take a little time to get acclimated to the offense.

E.J. Gaines (quadriceps) was a full participant in Wednesday's practice, Gary Klein of the Los Angeles Times reports.

Impact

Gaines has yet to play this season due to a quadriceps injury, but appears on track to change that in Sunday's matchup with the Cardinals. The third-year cornerback figures to provide depth in the secondary when he returns.

Head coach Mike McCoy said King Dunlap (illness) is "day-to-day with migraines", ESPN reports.

Impact

Dunlap was a mysterious inactive in Week 3, and while his ailment proved to be head-related, the migraines are reportedly not related to his extensive history with concussions. However, he did not practice on Wednesday and his status for Week 4 is far from certain.

Tavon Austin was limited at Wednesday's practice due to a shoulder injury, Rich Hammond of the Orange County Register reports.

Impact

Austin has been targeted a fair amount this season, and while his catch rate (14 of 29) falls short of 50 percent, he's sustained relevance due to his use as both a pass-catcher and rusher. Wednesday's limited practice is a tad concerning, but the fourth-year pro has two sessions remaining to allay fears about his Week 4 availability.

Drew Butler (ankle) did not participate at Wednesday's practice and is considered doubtful for Sunday's contest against the Rams, Mike Jurecki of Fox Sports 910 reports.

Impact

Butler was seen in a walking boot at Wednesday's practice, and while he may hold snaps for Chandler Catanzaro on Sunday, the chances of him punting against the Rams seem slim. If Butler sits, the Cardinals will need to look elsewhere to delegate punting responsibilities.

Michael Floyd (concussion) was limited at practice Wednesday, Mike Jurecki of FOX Sports 910 Phoenix reports.

Impact

After emerging from Sunday's loss at Buffalo with a concussion, Floyd has breezed through the NFL's protocol for head injuries. As evidence, head coach Bruce Arians stated Wednesday that Floyd completed Wednesday's practice in a yellow non-contact jersey, according to Darren Urban of the Cardinals' official site. Floyd must receive clearance from an independent neurologist in order to take part in all activity, but considering the progress made already, he could back up Arians' optimism outlook from Tuesday in which he stated a belief the wide receiver could reach that point by Thursday.

Robert Nkemdiche (ankle) was a full participant at Wednesday's practice, Mike Jurecki of Fox Sports 910 reports.

Impact

Nkemdiche's full workload at practice would indicate that his ankle injury is largely healed at this point, even though it caused him to miss Week 3's tilt against the Bills. All signs point to him being able to go Sunday against the Rams.

Nick Vannett (ankle) was a limited participant at Wednesday's practice, Bob Condotta of The Seattle Times reports.

Impact

Vannett has now been limited in two straight practices, which is a sign that he is making progress with his recovery from an ankle sprain. When he does return to game action, he will sit behind Jimmy Graham and Luke Willson at tight end and is unlikely to make any kind of fantasy impact.

Tyler Lockett (knee) was limited at Wednesday's practice, Bob Condotta of the Seattle Times reports.

Impact

Lockett similarly kicked off Week 3 prep with a limited showing and logged back-to-back full practice Thursday and Friday, only to go without a target in Sunday's convincing win against the 49ers. As the week proceeds, he could very well follow a similar schedule, but until he produces again, it's difficult to trust in the second-year wideout.

The Seahawks released Terrence Magee on Wednesday.

Impact

The team opted to sign free agent C.J. Spiller, and subsequently released Magee to make room on the roster. The 23-year-old had recently been promoted from the practice squad, had tallied 12 yards on three carries in their win over the 49ers on Sunday.

Jimmy Graham (knee) practiced in a limited capacity Wednesday, Bob Condotta of the Seattle Times reports.

Impact

Graham has slowly but surely increased his comfort within the offense through three games, culminating with six catches (on nine targets) for 100 yards and one touchdown this past Sunday against the 49ers. The development may be tied to putting last year's torn patellar tendon further in the rearview mirror, but San Francisco's defense has allowed the second-most yards (248) to opposing tight ends this season. With another friendly matchup on top in Week 4 – the Jets have conceded a 71-percent catch rate to TE – Graham is poised for back-to-back relevant outings.

Kamar Aiken (thigh) did not participate in Wednesday's practice.

Impact

When exactly Aiken suffered from the thigh ailment is currently unknown and there is currently no listed timetable. He should be considered questionable until his status is further updated in the next few days. Aiken is becoming irrelevant in the Ravens' offensive attack, managing just five catches in three games so far this season.

Menelik Watson (calf) did not participate in Wednesday's practice.

Impact

Watson was forced out of Sunday's win over the Titans after injuring his calf. Given his absence from practice, his status for Week 4 is seemingly up in the air. Austin Howard should fill in at right tackle if the 27-year-old cannot go.

Taiwan Jones (knee) did not practice on Wednesday.

Impact

Jones has been nursing a knee injury since Week 2, but has still managed to play in every contest this season. His status for Week 4 doesn't seem to be in any peril, though his participation in practice will certainly shed more light on his availability.